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Brand name: Talzenna

Chemical name: Talazoparib

Class: PARP inhibitor. Lynparza is another PARP inhibitor

How it works: The poly ADP-ribose polymerase (PARP) enzyme fixes DNA damage in both healthy and cancer cells. Research has shown that a medicine like Talzenna, which interferes with (inhibits) the PARP enzyme, makes it harder for cancer cells with a BRCA1 or BRCA2 mutation to fix DNA damage. This makes it even harder for the cancer cells to survive. In other words, a PARP inhibitor makes some cancer cells less likely to survive their DNA damage.

Uses: Talzenna is used to treat locally advanced or metastatic HER2-negative breast cancer with an inherited BRCA1 or BRCA2 mutation.

How it’s given: Talzenna is a pill taken by mouth.

Side effects:

Read more about Talzenna.

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