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Brand name: Tecentriq

Chemical name: Atezolizumab

Class: PD-L1 immune checkpoint inhibitor

How it works: PD-1 is a checkpoint protein on T cells, immune system cells that attack foreign invaders in the body. PD-L1 is another checkpoint protein found on many healthy cells in the body. When PD-1 binds to PD-L1, it stops T cells from killing a cell. Some cancer cells have a lot of PD-L1 on their surface, which stops T cells from killing these cancer cells. These cancers are called PD-L1-positive. An immune checkpoint inhibitor medicine such as Tecentriq that stops PD-1 from binding to PD-L1 allows T cells to attack the cancer cells.

Uses: Tecentriq may be used in combination with the chemotherapy medicine Abraxane (chemical name: albumin-bound or nab-paclitaxel) to treat unresectable locally advanced or metastatic triple-negative, PD-L1-positive breast cancer.

How it’s given: Tecentriq is given intravenously.

Side effects:

Read more about Tecentriq.

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