Brand name: Tukysa
Chemical name: Tucatinib
Class: Tyrosine kinase inhibitor
How it works: Tyrosine kinases are enzymes that help control how cells grow and divide, among other functions. If the enzyme is too active or if a cell has too much of the enzyme, it can make cells grow uncontrollably. Tukysa blocks a specific area of the HER2 gene in cancer cells, which stops the cells from growing and spreading.
Uses: Tukysa is used in combination with Herceptin (chemical name: trastuzumab) and Xeloda (chemical name: capecitabine) to treat metastatic HER2-positive breast cancer or locally advanced HER2-positive disease that can’t be completely removed with surgery, after the cancer has been treated with at least one anti-HER2 medicine.
How it’s given: Tukysa is a pill taken by mouth.
- hand-foot syndrome
- liver problems
- mouth sores
- decreased appetite
- abdominal pain
Read more about Tukysa.
- Tukysa (tucatinib) prescribing information. Seattle Genetics, Inc. Bothell, WA. 2020. Available at: https://seagendocs.com/TUKYSA_Full_Ltr_Master.pdf (PDF)
Can we help guide you?
Create a profile for better recommendations
Breast self-exam, or regularly examining your breasts on your own, can be an important way to...
Tamoxifen (Brand Names: Nolvadex, Soltamox)
Tamoxifen is the oldest and most-prescribed selective estrogen receptor modulator (SERM)....
Breast Cancer Stages
The stage of a breast cancer is determined by the cancer’s characteristics, such as how large it...